6MN1
Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA
Summary for 6MN1
Entry DOI | 10.2210/pdb6mn1/pdb |
Related | 5HT0 |
Descriptor | Aminoglycoside N(3)-acetyltransferase, COENZYME A, (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, ... (8 entities in total) |
Functional Keywords | antibiotic_nat family, acetyltransferase, aminoglycoside, antibiotic resistance, metagenome, soil, coenzyme a, csgid, transferase, center for structural genomics of infectious diseases, national institute of allergy and infectious diseases, niaid, transferase-antibiotic complex, transferase/antibiotic |
Biological source | uncultured bacterium |
Total number of polymer chains | 2 |
Total formula weight | 62112.17 |
Authors | Stogios, P.J.,Skarina, T.,Michalska, K.,Xu, Z.,Yim, V.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-10-01, release date: 2018-10-24, Last modification date: 2023-10-11) |
Primary citation | Stogios, P.J. Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in abortive complex with gentamicin-CoA To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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