6MLR
Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state
Summary for 6MLR
Entry DOI | 10.2210/pdb6mlr/pdb |
EMDB information | 9141 |
Descriptor | Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein KIF7, ... (7 entities in total) |
Functional Keywords | microtubule tip-tracking, primary cilium, hedgehog signaling, motor protein, motor protein-inhibitor complex, motor protein/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 146018.78 |
Authors | Mani, N.,Jiang, S.,Wilson-Kubalek, E.M.,Ku, P.,Milligan, R.A.,Subramanian, R. (deposition date: 2018-09-27, release date: 2019-05-01, Last modification date: 2024-03-13) |
Primary citation | Jiang, S.,Mani, N.,Wilson-Kubalek, E.M.,Ku, P.I.,Milligan, R.A.,Subramanian, R. Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Dev.Cell, 49:711-730.e8, 2019 Cited by PubMed: 31031197DOI: 10.1016/j.devcel.2019.04.001 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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