6MLJ

Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S70A mutant from Salmonella typhimurium complexed with arginine

Summary for 6MLJ

Entry DOI	10.2210/pdb6mlj/pdb
Related	6MKU 6MKW 6MKX 6ML0 6ML9 6MLA 6MLD 6MLE 6MLG 6MLI 6MLN 6MLO 6MLP 6MLV
Descriptor	Lysine/arginine/ornithine transport protein, ARGININE, ACETATE ION, ... (4 entities in total)
Functional Keywords	periplasmic binding protein, lao, thermodynamics, protein ligand complex, protein binding
Biological source	Salmonella typhimurium (strain 14028s / SGSC 2262)
Total number of polymer chains	2
Total formula weight	52351.93
Authors	Romero-Romero, S.,Vergara, R.,Espinoza-Perez, G.,Rodriguez-Romero, A. (deposition date: 2018-09-27, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Vergara, R.,Romero-Romero, S.,Velazquez-Lopez, I.,Espinoza-Perez, G.,Rodriguez-Hernandez, A.,Pulido, N.O.,Sosa-Peinado, A.,Rodriguez-Romero, A.,Fernandez-Velasco, D.A. The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287:763-782, 2020 Cited by PubMed: 31348608 DOI: 10.1111/febs.15019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation