6MLC

PHD6 domain of MLL3 in complex with histone H4

Summary for 6MLC

Entry DOI	10.2210/pdb6mlc/pdb
Descriptor	Histone-lysine N-methyltransferase 2C, Histone H4, ZINC ION, ... (6 entities in total)
Functional Keywords	mll3, phd6, structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	47390.14
Authors	Dong, A.,Liu, Y.,Qin, S.,Lei, M.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-09-27, release date: 2018-10-24, Last modification date: 2024-03-13)
Primary citation	Liu, Y.,Qin, S.,Chen, T.Y.,Lei, M.,Dhar, S.S.,Ho, J.C.,Dong, A.,Loppnau, P.,Li, Y.,Lee, M.G.,Min, J. Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun, 10:36-36, 2019 Cited by PubMed: 30604749 DOI: 10.1038/s41467-018-07906-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation