6MKZ
Crystal structure of murine 4-1BB/4-1BBL complex
Summary for 6MKZ
Entry DOI | 10.2210/pdb6mkz/pdb |
Descriptor | Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | tnf, tnfr, signaling protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 69984.75 |
Authors | Bitra, A.,Zajonc, D.M.,Doukov, T. (deposition date: 2018-09-26, release date: 2018-12-19, Last modification date: 2023-10-11) |
Primary citation | Bitra, A.,Doukov, T.,Destito, G.,Croft, M.,Zajonc, D.M. Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding. J. Biol. Chem., 294:1831-1845, 2019 Cited by PubMed: 30545939DOI: 10.1074/jbc.RA118.006297 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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