6MKG

Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the benzylpenicilin-bound form

Summary for 6MKG

• Entry DOI: 10.2210/pdb6mkg/pdb
• Descriptor: penicillin binding protein 5 (PBP5), OPEN FORM - PENICILLIN G, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transpeptidase, pbp5, peptide binding protein, protein binding-antibiotic complex, protein binding/antibiotic
• Biological source: Enterococcus faecium
• Total number of polymer chains: 1
• Total formula weight: 76273.97

Authors

Moon, T.M.,Lee, C.,D'Andrea, E.D.,Peti, W.,Page, R. (deposition date: 2018-09-25, release date: 2018-10-31, Last modification date: 2024-04-03)

• Primary citation: Moon, T.M.,D'Andrea, E.D.,Lee, C.W.,Soares, A.,Jakoncic, J.,Desbonnet, C.,Garcia-Solache, M.,Rice, L.B.,Page, R.,Peti, W.; The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.; J. Biol. Chem., 293:18574-18584, 2018; PubMed: 30355734; DOI: 10.1074/jbc.RA118.006052

Experimental method

X-RAY DIFFRACTION (2.94 Å)