6MKF
Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the imipenem-bound form
Summary for 6MKF
Entry DOI | 10.2210/pdb6mkf/pdb |
Descriptor | penicillin binding protein 5 (PBP5), (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transpeptidase, pbp, penicillin-binding protein, protein binding-antibiotic complex, protein binding/antibiotic |
Biological source | Enterococcus faecium |
Total number of polymer chains | 1 |
Total formula weight | 71601.09 |
Authors | Moon, T.M.,Lee, C.,D'Andrea, E.D.,Peti, W.,Page, R. (deposition date: 2018-09-25, release date: 2018-10-31, Last modification date: 2024-04-03) |
Primary citation | Moon, T.M.,D'Andrea, E.D.,Lee, C.W.,Soares, A.,Jakoncic, J.,Desbonnet, C.,Garcia-Solache, M.,Rice, L.B.,Page, R.,Peti, W. The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance. J. Biol. Chem., 293:18574-18584, 2018 Cited by PubMed: 30355734DOI: 10.1074/jbc.RA118.006052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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