6MKB

Crystal structure of murine 4-1BB ligand

6MKB の概要

• エントリーDOI: 10.2210/pdb6mkb/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 9, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: tnf, signaling protein, dimer
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 80935.76

構造登録者

Bitra, A.,Zajonc, D.M.,Doukov, T. (登録日: 2018-09-25, 公開日: 2018-12-19, 最終更新日: 2023-10-11)

• 主引用文献: Bitra, A.,Doukov, T.,Destito, G.,Croft, M.,Zajonc, D.M.; Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.; J. Biol. Chem., 294:1831-1845, 2019; PubMed: 30545939; DOI: 10.1074/jbc.RA118.006297

実験手法

X-RAY DIFFRACTION (2.5 Å)