6MI0
Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, ligand-free state
Summary for 6MI0
Entry DOI | 10.2210/pdb6mi0/pdb |
Descriptor | Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total) |
Functional Keywords | cytochrome p450 fold, cyp51, heme, sterol biosynthesis, oxidoreductase |
Biological source | Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) |
Total number of polymer chains | 1 |
Total formula weight | 52363.25 |
Authors | Hargrove, T.,Wawrzak, Z.,Lamb, D.C.,Lepesheva, G.I. (deposition date: 2018-09-18, release date: 2019-07-10, Last modification date: 2023-10-11) |
Primary citation | Lamb, D.C.,Hargrove, T.Y.,Zhao, B.,Wawrzak, Z.,Goldstone, J.V.,Nes, W.D.,Kelly, S.L.,Waterman, M.R.,Stegeman, J.J.,Lepesheva, G.I. Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases. Mol.Biol.Evol., 2020 Cited by PubMed: 33031537DOI: 10.1093/molbev/msaa260 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.73 Å) |
Structure validation
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