6MGN
mouse Id1 (51-104) - human hE47 (348-399) complex
Summary for 6MGN
Entry DOI | 10.2210/pdb6mgn/pdb |
Descriptor | Transcription factor E2-alpha, DNA-binding protein inhibitor ID-1 (3 entities in total) |
Functional Keywords | dna-binding protein inhibitor id-1, transcription factor e2-alpha isoform e47 [homo sapiens], dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 11726.70 |
Authors | Benezra, R.,Pavletich, N.P.,Gall, A.-L.,Goldgur, Y. (deposition date: 2018-09-14, release date: 2019-09-18, Last modification date: 2023-10-11) |
Primary citation | Wojnarowicz, P.M.,Lima E Silva, R.,Ohnaka, M.,Lee, S.B.,Chin, Y.,Kulukian, A.,Chang, S.H.,Desai, B.,Garcia Escolano, M.,Shah, R.,Garcia-Cao, M.,Xu, S.,Kadam, R.,Goldgur, Y.,Miller, M.A.,Ouerfelli, O.,Yang, G.,Arakawa, T.,Albanese, S.K.,Garland, W.A.,Stoller, G.,Chaudhary, J.,Norton, L.,Soni, R.K.,Philip, J.,Hendrickson, R.C.,Iavarone, A.,Dannenberg, A.J.,Chodera, J.D.,Pavletich, N.,Lasorella, A.,Campochiaro, P.A.,Benezra, R. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep, 29:62-75.e7, 2019 Cited by PubMed: 31577956DOI: 10.1016/j.celrep.2019.08.073 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.901 Å) |
Structure validation
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