6MG3
V285A Mutant of the C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence
Summary for 6MG3
Entry DOI | 10.2210/pdb6mg3/pdb |
Descriptor | CCAAT/enhancer-binding protein beta, 16-bp methylated oligonucleotide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | bzip transciption factor dna methylation cpa methylation protein-dna complex, transcription, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 28505.99 |
Authors | Horton, J.R.,Cheng, X.,Yang, J. (deposition date: 2018-09-12, release date: 2018-12-12, Last modification date: 2023-10-11) |
Primary citation | Yang, J.,Horton, J.R.,Wang, D.,Ren, R.,Li, J.,Sun, D.,Huang, Y.,Zhang, X.,Blumenthal, R.M.,Cheng, X. Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47:1774-1785, 2019 Cited by PubMed: 30566668DOI: 10.1093/nar/gky1264 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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