6MDT

Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space group

Summary for 6MDT

• Entry DOI: 10.2210/pdb6mdt/pdb
• Related: 6MCO
• Descriptor: Transmembrane protein gp41, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• Functional Keywords: viral protein, hiv, envelope, glycoprotein, prefusion trimer, glycan, hiv-1 gp120, hiv-1 gp41, n332 supersite, immune system, neutralizing antibodies, complex, viral protein-immune system complex
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 6
• Total formula weight: 182803.56

Authors

Kumar, S.,Sarkar, A.,Wilson, I.A. (deposition date: 2018-09-05, release date: 2019-02-27, Last modification date: 2023-10-11)

• Primary citation: Kumar, S.,Sarkar, A.,Pugach, P.,Sanders, R.W.,Moore, J.P.,Ward, A.B.,Wilson, I.A.; Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.; Nat Commun, 10:763-763, 2019; PubMed: 30770829; DOI: 10.1038/s41467-019-08738-5

Experimental method

X-RAY DIFFRACTION (3.816 Å)