6MDT

Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space group

6MDT の概要

• エントリーDOI: 10.2210/pdb6mdt/pdb
• 関連するPDBエントリー: 6MCO
• 分子名称: Transmembrane protein gp41, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total)
• 機能のキーワード: viral protein, hiv, envelope, glycoprotein, prefusion trimer, glycan, hiv-1 gp120, hiv-1 gp41, n332 supersite, immune system, neutralizing antibodies, complex, viral protein-immune system complex
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 182803.56

構造登録者

Kumar, S.,Sarkar, A.,Wilson, I.A. (登録日: 2018-09-05, 公開日: 2019-02-27, 最終更新日: 2023-10-11)

• 主引用文献: Kumar, S.,Sarkar, A.,Pugach, P.,Sanders, R.W.,Moore, J.P.,Ward, A.B.,Wilson, I.A.; Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.; Nat Commun, 10:763-763, 2019; PubMed: 30770829; DOI: 10.1038/s41467-019-08738-5

実験手法

X-RAY DIFFRACTION (3.816 Å)