6MD0
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Oleic Acid
Summary for 6MD0
Entry DOI | 10.2210/pdb6md0/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, OLEIC ACID (3 entities in total) |
Functional Keywords | nuclear receptors, tzds, drug design, therapeutic targets, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 63463.96 |
Authors | Shang, J.,Kojetin, D.J. (deposition date: 2018-09-03, release date: 2019-01-09, Last modification date: 2023-10-11) |
Primary citation | Shang, J.,Brust, R.,Mosure, S.A.,Bass, J.,Munoz-Tello, P.,Lin, H.,Hughes, T.S.,Tang, M.,Ge, Q.,Kamekencka, T.M.,Kojetin, D.J. Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7:-, 2018 Cited by PubMed: 30575522DOI: 10.7554/eLife.43320 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)