6MAY

Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax

Summary for 6MAY

Entry DOI	10.2210/pdb6may/pdb
Descriptor	Glycylpeptide N-tetradecanoyltransferase, TETRADEC-13-YNOIC ACID - COA THIOESTER, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	ssgcid, glycylpeptide n-tetradecanoyltransferase, n-myristoyltransferase, nmt, plasmodium vivax, salvador i, structural genomics, seattle structural genomics center for infectious disease, transferase
Biological source	Plasmodium vivax
Total number of polymer chains	3
Total formula weight	145437.35
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-08-29, release date: 2019-06-05, Last modification date: 2024-03-13)
Primary citation	Schlott, A.C.,Mayclin, S.,Reers, A.R.,Coburn-Flynn, O.,Bell, A.S.,Green, J.,Knuepfer, E.,Charter, D.,Bonnert, R.,Campo, B.,Burrows, J.,Lyons-Abbott, S.,Staker, B.L.,Chung, C.W.,Myler, P.J.,Fidock, D.A.,Tate, E.W.,Holder, A.A. Structure-Guided Identification of Resistance Breaking Antimalarial N‐Myristoyltransferase Inhibitors. Cell Chem Biol, 26:991-, 2019 Cited by PubMed: 31080074 DOI: 10.1016/j.chembiol.2019.03.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation