6M8H

Crystal Structure of the R208Q mutant of G(i) subunit alpha-1

Summary for 6M8H

• Entry DOI: 10.2210/pdb6m8h/pdb
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: g protein, switch ii region, oncogenic mutation, signaling protein
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 1
• Total formula weight: 40933.52

Authors

Mascarenhas, R.,Goossens, J.,Leverson, B.,Kothawala, S.,Ballicora, M.,Olsen, K.,de freitas, D.,Liu, D. (deposition date: 2018-08-21, release date: 2019-08-21, Last modification date: 2024-03-13)

• Primary citation: Goossens, J.L.,Leverson, B.D.,Kothawala, S.,Mascarenhas, R.,Liu, D.,Ballicora, M.,Olsen, K.W.,de Freitas, D.M.; FUNCTIONAL CONSEQUENCES OF ONCOGENIC MUTATIONS IN THE SWITCH II REGION OF Galphai1 and Galphas PROTEINS; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)