6M8H

Crystal Structure of the R208Q mutant of G(i) subunit alpha-1

6M8H の概要

• エントリーDOI: 10.2210/pdb6m8h/pdb
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: g protein, switch ii region, oncogenic mutation, signaling protein
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40933.52

構造登録者

Mascarenhas, R.,Goossens, J.,Leverson, B.,Kothawala, S.,Ballicora, M.,Olsen, K.,de freitas, D.,Liu, D. (登録日: 2018-08-21, 公開日: 2019-08-21, 最終更新日: 2024-03-13)

• 主引用文献: Goossens, J.L.,Leverson, B.D.,Kothawala, S.,Mascarenhas, R.,Liu, D.,Ballicora, M.,Olsen, K.W.,de Freitas, D.M.; FUNCTIONAL CONSEQUENCES OF ONCOGENIC MUTATIONS IN THE SWITCH II REGION OF Galphai1 and Galphas PROTEINS; To Be Published,

実験手法

X-RAY DIFFRACTION (2.07 Å)