6M7O

Human DNA polymerase eta ternary complex with Mn2+ and dTMPNPP oppositing cdA

Summary for 6M7O

• Entry DOI: 10.2210/pdb6m7o/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*AP*GP*TP*GP*TP*GP*AP*G*(1FZ))-3'), ... (6 entities in total)
• Functional Keywords: translesion synthesis, cda, dna binding protein, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 54990.59

Authors

Weng, P.,Gao, Y.,Yang, W. (deposition date: 2018-08-20, release date: 2018-09-12, Last modification date: 2023-10-11)

• Primary citation: Weng, P.J.,Gao, Y.,Gregory, M.T.,Wang, P.,Wang, Y.,Yang, W.; Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution.; Proc. Natl. Acad. Sci. U.S.A., 115:10660-10665, 2018; PubMed: 30275308; DOI: 10.1073/pnas.1812856115

Experimental method

X-RAY DIFFRACTION (3 Å)