6M4T
U shaped head to head four-way junction in d(TTCTGCTGCTGAA) sequence
Summary for 6M4T
Entry DOI | 10.2210/pdb6m4t/pdb |
Descriptor | DNA (5'-D(P*(UD)P*TP*CP*TP*GP*CP*TP*GP*CP*TP*GP*AP*A)-3'), COBALT (II) ION, N4-[4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]butyl]-1,3,5-triazine-2,4,6-triamine, ... (4 entities in total) |
Functional Keywords | t:t mismatch, ctg repeat, four-way junction, triaminotriazine-acridine conjugate, dna |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 18081.20 |
Authors | Hou, M.H.,Chien, C.M.,Satange, R.B.,Wu, P.C. (deposition date: 2020-03-09, release date: 2020-07-15, Last modification date: 2024-03-27) |
Primary citation | Chien, C.M.,Wu, P.C.,Satange, R.,Chang, C.C.,Lai, Z.L.,Hagler, L.D.,Zimmerman, S.C.,Hou, M.H. Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA. J.Am.Chem.Soc., 142:11165-11172, 2020 Cited by PubMed: 32478511DOI: 10.1021/jacs.0c03591 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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