6M4T

U shaped head to head four-way junction in d(TTCTGCTGCTGAA) sequence

Summary for 6M4T

• Entry DOI: 10.2210/pdb6m4t/pdb
• Descriptor: DNA (5'-D(P*(UD)P*TP*CP*TP*GP*CP*TP*GP*CP*TP*GP*AP*A)-3'), COBALT (II) ION, N4-[4-[(6-chloranyl-2-methoxy-acridin-9-yl)amino]butyl]-1,3,5-triazine-2,4,6-triamine, ... (4 entities in total)
• Functional Keywords: t:t mismatch, ctg repeat, four-way junction, triaminotriazine-acridine conjugate, dna
• Biological source: synthetic construct
• Total number of polymer chains: 4
• Total formula weight: 18081.20

Authors

Hou, M.H.,Chien, C.M.,Satange, R.B.,Wu, P.C. (deposition date: 2020-03-09, release date: 2020-07-15, Last modification date: 2024-03-27)

• Primary citation: Chien, C.M.,Wu, P.C.,Satange, R.,Chang, C.C.,Lai, Z.L.,Hagler, L.D.,Zimmerman, S.C.,Hou, M.H.; Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA.; J.Am.Chem.Soc., 142:11165-11172, 2020; PubMed: 32478511; DOI: 10.1021/jacs.0c03591

Experimental method

X-RAY DIFFRACTION (1.55 Å)