6LUI
Crystal structure of the SAMD1 WH domain and DNA complex
Summary for 6LUI
Entry DOI | 10.2210/pdb6lui/pdb |
Descriptor | Atherin, DNA (5'-D(*AP*CP*CP*TP*GP*CP*GP*CP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*GP*TP*GP*CP*GP*CP*AP*GP*GP*T)-3'), ... (4 entities in total) |
Functional Keywords | cpg islands; transcription; polycomb, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 17477.98 |
Authors | |
Primary citation | Stielow, B.,Zhou, Y.,Cao, Y.,Simon, C.,Pogoda, H.M.,Jiang, J.,Ren, Y.,Phanor, S.K.,Rohner, I.,Nist, A.,Stiewe, T.,Hammerschmidt, M.,Shi, Y.,Bulyk, M.L.,Wang, Z.,Liefke, R. The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands. Sci Adv, 7:-, 2021 Cited by PubMed: 33980486DOI: 10.1126/sciadv.abf2229 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.781 Å) |
Structure validation
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