6LUI

Crystal structure of the SAMD1 WH domain and DNA complex

Summary for 6LUI

• Entry DOI: 10.2210/pdb6lui/pdb
• Descriptor: Atherin, DNA (5'-D(*AP*CP*CP*TP*GP*CP*GP*CP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*GP*TP*GP*CP*GP*CP*AP*GP*GP*T)-3'), ... (4 entities in total)
• Functional Keywords: cpg islands; transcription; polycomb, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 17477.98

Authors

Zhou, Y.,Cao, Y.,Wang, Z. (deposition date: 2020-01-29, release date: 2021-02-03, Last modification date: 2021-07-07)

• Primary citation: Stielow, B.,Zhou, Y.,Cao, Y.,Simon, C.,Pogoda, H.M.,Jiang, J.,Ren, Y.,Phanor, S.K.,Rohner, I.,Nist, A.,Stiewe, T.,Hammerschmidt, M.,Shi, Y.,Bulyk, M.L.,Wang, Z.,Liefke, R.; The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.; Sci Adv, 7:-, 2021; PubMed: 33980486; DOI: 10.1126/sciadv.abf2229

Experimental method

X-RAY DIFFRACTION (1.781 Å)