6LTW
Crystal structure of Apo form of I122A/I330A variant of S-adenosylmethionine synthetase from Cryptosporidium hominis
Summary for 6LTW
| Entry DOI | 10.2210/pdb6ltw/pdb |
| Descriptor | S-adenosylmethionine synthase, MAGNESIUM ION, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | mutanat, methionine adenosyltransferase, transferase |
| Biological source | Cryptosporidium hominis |
| Total number of polymer chains | 2 |
| Total formula weight | 92219.43 |
| Authors | Singh, R.K.,Michailidou, F.,Rentmeister, A.,Kuemmel, D. (deposition date: 2020-01-23, release date: 2020-10-21, Last modification date: 2023-11-29) |
| Primary citation | Michailidou, F.,Klocker, N.,Cornelissen, N.V.,Singh, R.K.,Peters, A.,Ovcharenko, A.,Kummel, D.,Rentmeister, A. Engineered SAM Synthetases for Enzymatic Generation of AdoMet Analogs with Photocaging Groups and Reversible DNA Modification in Cascade Reactions. Angew.Chem.Int.Ed.Engl., 60:480-485, 2021 Cited by PubMed: 33017502DOI: 10.1002/anie.202012623 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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