6LTW

Crystal structure of Apo form of I122A/I330A variant of S-adenosylmethionine synthetase from Cryptosporidium hominis

6LTW の概要

• エントリーDOI: 10.2210/pdb6ltw/pdb
• 分子名称: S-adenosylmethionine synthase, MAGNESIUM ION, PHOSPHATE ION, ... (4 entities in total)
• 機能のキーワード: mutanat, methionine adenosyltransferase, transferase
• 由来する生物種: Cryptosporidium hominis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92219.43

構造登録者

Singh, R.K.,Michailidou, F.,Rentmeister, A.,Kuemmel, D. (登録日: 2020-01-23, 公開日: 2020-10-21, 最終更新日: 2023-11-29)

• 主引用文献: Michailidou, F.,Klocker, N.,Cornelissen, N.V.,Singh, R.K.,Peters, A.,Ovcharenko, A.,Kummel, D.,Rentmeister, A.; Engineered SAM Synthetases for Enzymatic Generation of AdoMet Analogs with Photocaging Groups and Reversible DNA Modification in Cascade Reactions.; Angew.Chem.Int.Ed.Engl., 60:480-485, 2021; PubMed: 33017502; DOI: 10.1002/anie.202012623

実験手法

X-RAY DIFFRACTION (1.65 Å)