6LPU
Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with L-2-hydroxyglutarate (L-2-HG)
Summary for 6LPU
Entry DOI | 10.2210/pdb6lpu/pdb |
Descriptor | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (4 entities in total) |
Functional Keywords | dehydrogenase, flavoprotein, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 106663.90 |
Authors | |
Primary citation | Yang, J.,Zhu, H.,Zhang, T.,Ding, J. Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7:3-3, 2021 Cited by PubMed: 33431826DOI: 10.1038/s41421-020-00227-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.923 Å) |
Structure validation
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