6LO2
Crystal structure of EED in complex with EZH2 peptide and compound 11#
Summary for 6LO2
Entry DOI | 10.2210/pdb6lo2/pdb |
Descriptor | Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, 8-[4-[(dimethylamino)methyl]phenyl]-N-[(2-methoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-5-amine, ... (4 entities in total) |
Functional Keywords | hts hit optimization, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 92731.78 |
Authors | |
Primary citation | Zhao, K.,Zhao, M.,Luo, X.,Zhang, H. Structure of EED in complex with EZH2 peptide and cmpd20 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)