6LML

Cryo-EM structure of the human glucagon receptor in complex with Gi1

6LML の概要

• エントリーDOI: 10.2210/pdb6lml/pdb
• EMDBエントリー: 0918
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: glucagon receptor, gpcr, gi1 protein, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 165415.06

構造登録者

Qiao, A.,Han, S.,Li, X.,Sun, F.,Zhao, Q.,Wu, B. (登録日: 2019-12-26, 公開日: 2020-04-01)

• 主引用文献: Qiao, A.,Han, S.,Li, X.,Li, Z.,Zhao, P.,Dai, A.,Chang, R.,Tai, L.,Tan, Q.,Chu, X.,Ma, L.,Thorsen, T.S.,Reedtz-Runge, S.,Yang, D.,Wang, M.W.,Sexton, P.M.,Wootten, D.,Sun, F.,Zhao, Q.,Wu, B.; Structural basis of Gsand Girecognition by the human glucagon receptor.; Science, 367:1346-1352, 2020; PubMed: 32193322; DOI: 10.1126/science.aaz5346

実験手法

ELECTRON MICROSCOPY (3.9 Å)