6LJL
Crystal Structure of exoHep-Y390A/H555A complexed with a tetrasaccharide substrate
Summary for 6LJL
Entry DOI | 10.2210/pdb6ljl/pdb |
Descriptor | Heparinase II/III-like protein, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | heparin, heparan sulfate, heparinase, crystall, lyase |
Biological source | Bacteroides intestinalis DSM 17393 |
Total number of polymer chains | 1 |
Total formula weight | 101053.33 |
Authors | Zhang, Q.D.,Cao, H.Y.,Wei, L.,Li, F.C.,Zhang, Y.Z. (deposition date: 2019-12-17, release date: 2020-12-23, Last modification date: 2023-11-22) |
Primary citation | Zhang, Q.,Cao, H.Y.,Wei, L.,Lu, D.,Du, M.,Yuan, M.,Shi, D.,Chen, X.,Wang, P.,Chen, X.L.,Chi, L.,Zhang, Y.Z.,Li, F. Discovery of exolytic heparinases and their catalytic mechanism and potential application. Nat Commun, 12:1263-1263, 2021 Cited by PubMed: 33627653DOI: 10.1038/s41467-021-21441-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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