6LHD

Crystal structure of p53/BCL-xL fusion complex

Summary for 6LHD

• Entry DOI: 10.2210/pdb6lhd/pdb
• Descriptor: fusion protein of Bcl-2-like protein 1 and Isoform 6 of Cellular tumor antigen p53, ZINC ION (3 entities in total)
• Functional Keywords: complex, interaction, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 83850.30

Authors

Wei, H.,Chen, Y. (deposition date: 2019-12-07, release date: 2021-03-31, Last modification date: 2023-11-22)

• Primary citation: Wei, H.,Qu, L.,Dai, S.,Li, Y.,Wang, H.,Feng, Y.,Chen, X.,Jiang, L.,Guo, M.,Li, J.,Chen, Z.,Chen, L.,Zhang, Y.,Chen, Y.; Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.; Nat Commun, 12:2280-2280, 2021; PubMed: 33863900; DOI: 10.1038/s41467-021-22655-6

Experimental method

X-RAY DIFFRACTION (2.499 Å)