6LG9
crystal structure of the first bromodomain of human BRD4 in complex with compound BDF-2143
Summary for 6LG9
Entry DOI | 10.2210/pdb6lg9/pdb |
Descriptor | Bromodomain-containing protein 4, 2-azanyl-7-bromanyl-4-imidazol-1-yl-quinolin-8-ol (3 entities in total) |
Functional Keywords | brd4, inhibitor, complex, dna binding protein, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15188.32 |
Authors | |
Primary citation | Xu, H.,Zuo, Y.,Luo, C.,Zhang, H. Lead-Opt: An efficient tool for structural optimization of lead compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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