6LE8

Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1

Summary for 6LE8

• Entry DOI: 10.2210/pdb6le8/pdb
• Descriptor: Probable endochitinase, (4R)-4-(4-ethoxyphenyl)-3-(2-hydroxyphenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: nematode family i chitinase, hydrolase, inhibitor, gh18
• Biological source: Caenorhabditis elegans
• Total number of polymer chains: 1
• Total formula weight: 42818.84

Authors

Chen, Q.,Yang, Q.,Zhou, Y. (deposition date: 2019-11-24, release date: 2021-05-26, Last modification date: 2023-11-22)

• Primary citation: Chen, Q.,Yang, Q.,Zhou, Y.; Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.39909326225 Å)