6LDP

Structure of CDK5R1-bound FEM1C

Summary for 6LDP

• Entry DOI: 10.2210/pdb6ldp/pdb
• Descriptor: Protein fem-1 homolog C,Peptide from Cyclin-dependent kinase 5 activator 1, SULFATE ION (3 entities in total)
• Functional Keywords: ubiquitination e3 ligase, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 91610.71

Authors

Chen, X.,Liao, S.,Xu, C. (deposition date: 2019-11-22, release date: 2020-10-21, Last modification date: 2024-03-20)

• Primary citation: Chen, X.,Liao, S.,Makaros, Y.,Guo, Q.,Zhu, Z.,Krizelman, R.,Dahan, K.,Tu, X.,Yao, X.,Koren, I.,Xu, C.; Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.; Nat.Chem.Biol., 17:254-262, 2021; PubMed: 33398168; DOI: 10.1038/s41589-020-00704-3

Experimental method

X-RAY DIFFRACTION (2.35 Å)