6LCY
Crystal structure of Synaptotagmin-7 C2B in complex with IP6
Summary for 6LCY
Entry DOI | 10.2210/pdb6lcy/pdb |
Descriptor | Synaptotagmin-7, INOSITOL HEXAKISPHOSPHATE (3 entities in total) |
Functional Keywords | synaptotagmin-7, ip6, insulin secretion, exocytosis |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 17775.28 |
Authors | |
Primary citation | Zhang, X.,Li, N.,Zhang, J.,Zhang, Y.,Yang, X.,Luo, Y.,Zhang, B.,Xu, Z.,Zhu, Z.,Yang, X.,Yan, Y.,Lin, B.,Wang, S.,Chen, D.,Ye, C.,Ding, Y.,Lou, M.,Wu, Q.,Hou, Z.,Zhang, K.,Liang, Z.,Wei, A.,Wang, B.,Wang, C.,Jiang, N.,Zhang, W.,Xiao, G.,Ma, C.,Ren, Y.,Qi, X.,Han, W.,Wang, C.,Rao, F. 5-IP 7 is a GPCR messenger mediating neural control of synaptotagmin-dependent insulin exocytosis and glucose homeostasis. Nat Metab, 3:1400-1414, 2021 Cited by PubMed: 34663975DOI: 10.1038/s42255-021-00468-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.301 Å) |
Structure validation
Download full validation report