6LB6
Crystal structure of dimeric RXR-LBD complexed with partial agonist NEt-4IB and TIF2 co-activator
Summary for 6LB6
Entry DOI | 10.2210/pdb6lb6/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 6-[ethyl-[4-(2-methylpropoxy)-3-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid, ... (4 entities in total) |
Functional Keywords | nuclear receptor, retinoid x receptor alpha, active form, co-factors, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 29060.62 |
Authors | Imai, D.,Numoto, N.,Nakano, S.,Kakuta, H.,Ito, N. (deposition date: 2019-11-13, release date: 2020-11-18, Last modification date: 2023-11-22) |
Primary citation | Imai, D.,Numoto, N.,Nakano, S.,Kakuta, H.,Ito, N. Crystal structure of dimeric RXR-LBD complexed with partial agonist NEt-4IB and TIF2 co-activator To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report