6L70
Complex structure of PEDV 3CLpro with GC376
Summary for 6L70
Entry DOI | 10.2210/pdb6l70/pdb |
Descriptor | PEDV main protease, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid (3 entities in total) |
Functional Keywords | 3c-like protease, complex, hydrolase |
Biological source | Porcine epidemic diarrhea virus |
Total number of polymer chains | 2 |
Total formula weight | 67562.38 |
Authors | Ye, G.,Peng, G.Q. (deposition date: 2019-10-30, release date: 2020-04-29, Last modification date: 2023-11-22) |
Primary citation | Ye, G.,Wang, X.,Tong, X.,Shi, Y.,Fu, Z.F.,Peng, G. Structural Basis for Inhibiting Porcine Epidemic Diarrhea Virus Replication with the 3C-Like Protease Inhibitor GC376. Viruses, 12:-, 2020 Cited by PubMed: 32098094DOI: 10.3390/v12020240 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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