6L63
Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC residues
Summary for 6L63
Entry DOI | 10.2210/pdb6l63/pdb |
Related PRD ID | PRD_900017 |
Descriptor | Coagulation factor XII, F3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | enzyme, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 57925.96 |
Authors | Sengoku, T.,Katoh, T.,Hirata, K.,Suga, H.,Ogata, K. (deposition date: 2019-10-26, release date: 2020-09-02, Last modification date: 2023-11-22) |
Primary citation | Katoh, T.,Sengoku, T.,Hirata, K.,Ogata, K.,Suga, H. Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic beta-amino acids. Nat.Chem., 12:1081-1088, 2020 Cited by PubMed: 32839601DOI: 10.1038/s41557-020-0525-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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