6L57

Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT , Mg and ATP binding at allosteric site.

6L57 の概要

• エントリーDOI: 10.2210/pdb6l57/pdb
• 分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: tca cycle, nad-isocitrate dehydrogenase, oxidoreductase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76848.26

構造登録者

Sun, P.,Ding, J. (登録日: 2019-10-22, 公開日: 2020-04-29, 最終更新日: 2023-11-22)

• 主引用文献: Sun, P.,Bai, T.,Ma, T.,Ding, J.; Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.; Sci Rep, 10:6225-6225, 2020; PubMed: 32277159; DOI: 10.1038/s41598-020-63425-6

実験手法

X-RAY DIFFRACTION (2.302 Å)