6L4S
cryo-em structure of alpha-synuclein fiber mutation type E46K
Summary for 6L4S
Entry DOI | 10.2210/pdb6l4s/pdb |
EMDB information | 0833 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | alpha-syn fiber, parkinson disease, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 32412.94 |
Authors | |
Primary citation | Zhao, K.,Li, Y.,Liu, Z.,Long, H.,Zhao, C.,Luo, F.,Sun, Y.,Tao, Y.,Su, X.D.,Li, D.,Li, X.,Liu, C. Parkinson's disease associated mutation E46K of alpha-synuclein triggers the formation of a distinct fibril structure. Nat Commun, 11:2643-2643, 2020 Cited by PubMed: 32457390DOI: 10.1038/s41467-020-16386-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.37 Å) |
Structure validation
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