6L0J

Crystal structure of Dihydroorotase in complex with malate at pH7.5 from Saccharomyces cerevisiae

Summary for 6L0J

• Entry DOI: 10.2210/pdb6l0j/pdb
• Related: 6L0A 6L0B 6L0F 6L0H 6L0l
• Descriptor: Dihydroorotase, ZINC ION, (2S)-2-hydroxybutanedioic acid, ... (4 entities in total)
• Functional Keywords: dihydropyrimidinase dihydroorotase metalloenzyme, hydrolase
• Biological source: Saccharomyces cerevisiae S288C (Baker's yeast)
• Total number of polymer chains: 4
• Total formula weight: 166973.04

Authors

Guan, H.H.,Huang, Y.H.,Huang, C.Y.,Chen, C.J. (deposition date: 2019-09-26, release date: 2020-12-02, Last modification date: 2023-11-22)

• Primary citation: Guan, H.H.,Huang, Y.H.,Lin, E.S.,Chen, C.J.,Huang, C.Y.; Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism; Molecules, 2021; DOI: 10.3390/molecules26237249

Experimental method

X-RAY DIFFRACTION (1.933 Å)