6KW1
The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide 1b
Summary for 6KW1
Entry DOI | 10.2210/pdb6kw1/pdb |
Descriptor | Beta-lactamase class B VIM-2, ZINC ION, CHLORIDE ION, ... (9 entities in total) |
Functional Keywords | antibiotic resistant, metallo-beta-lactamase vim-2 inhibitor, trizolylthioacetamides, crystallographic study, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 58248.64 |
Authors | Yang, K.W.,Xiang, Y. (deposition date: 2019-09-05, release date: 2020-09-09, Last modification date: 2023-11-22) |
Primary citation | Xiang, Y.,Zhang, Y.J.,Ge, Y.,Zhou, Y.,Chen, C.,Wahlgren, W.Y.,Tan, X.,Chen, X.,Yang, K.W. Kinetic, Thermodynamic, and Crystallographic Studies of 2-Triazolylthioacetamides as Verona Integron-Encoded Metallo-beta-Lactamase 2 (VIM-2) Inhibitor. Biomolecules, 10:-, 2020 Cited by PubMed: 31906402DOI: 10.3390/biom10010072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77521201035 Å) |
Structure validation
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