6KVP

S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)

6KVP の概要

• エントリーDOI: 10.2210/pdb6kvp/pdb
• 分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: gtpase, protein-inhibitor complex, hydrolase
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32827.51

構造登録者

Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Parhi, A.K.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S. (登録日: 2019-09-05, 公開日: 2020-01-15, 最終更新日: 2023-11-22)

• 主引用文献: Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Al-Tameemi, H.M.,Boyd, J.M.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S.; Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.; Sci Rep, 9:20092-20092, 2019; PubMed: 31882782; DOI: 10.1038/s41598-019-56557-x

実験手法

X-RAY DIFFRACTION (1.4 Å)