6KTQ

Crystal structure of catalytic domain of homocitrate synthase from Sulfolobus acidocaldarius (SaHCS(dRAM)) in complex with alpha-ketoglutarate/Zn2+/CoA

Summary for 6KTQ

• Entry DOI: 10.2210/pdb6ktq/pdb
• Descriptor: Homocitrate synthase, ZINC ION, 2-OXOGLUTARIC ACID, ... (7 entities in total)
• Functional Keywords: homocitrate synthase, sulfolobus acidocaldarius, complex, biosynthetic protein, lyase
• Biological source: Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
• Total number of polymer chains: 2
• Total formula weight: 94392.97

Authors

Suzuki, T.,Tomita, T.,Kuzuyama, T.,Nishiyama, M. (deposition date: 2019-08-28, release date: 2020-09-02, Last modification date: 2023-11-22)

• Primary citation: Suzuki, T.,Tomita, T.,Hirayama, K.,Suzuki, M.,Kuzuyama, T.,Nishiyama, M.; Involvement of subdomain II in the recognition of acetyl-CoA revealed by the crystal structure of homocitrate synthase from Sulfolobus acidocaldarius.; Febs J., 288:1975-1988, 2021; PubMed: 32897601; DOI: 10.1111/febs.15527

Experimental method

X-RAY DIFFRACTION (1.98 Å)