6KMH

The crystal structure of CASK/Mint1 complex

Summary for 6KMH

Entry DOI	10.2210/pdb6kmh/pdb
Descriptor	Peripheral plasma membrane protein CASK, Amyloid-beta A4 precursor protein-binding family A member 1, IODIDE ION, ... (5 entities in total)
Functional Keywords	cask-camk domain, mint1, cask-mint1 complex, hydrophobic interactions, structural protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	90428.03
Authors	Li, W.,Feng, W. (deposition date: 2019-07-31, release date: 2020-08-05, Last modification date: 2023-11-22)
Primary citation	Zhang, Z.,Li, W.,Yang, G.,Lu, X.,Qi, X.,Wang, S.,Cao, C.,Zhang, P.,Ren, J.,Zhao, J.,Zhang, J.,Hong, S.,Tan, Y.,Burchfield, J.,Yu, Y.,Xu, T.,Yao, X.,James, D.,Feng, W.,Chen, Z. CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion. Cell Discov, 6:92-92, 2020 Cited by PubMed: 33318489 DOI: 10.1038/s41421-020-00216-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation