6KJV

Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain

Summary for 6KJV

• Entry DOI: 10.2210/pdb6kjv/pdb
• Related: 5VEW
• Descriptor: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (4 entities in total)
• Functional Keywords: gpcr, seven-transmembrane, allosteric modulators, diabetes, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 106910.74

Authors

Song, G. (deposition date: 2019-07-23, release date: 2019-11-13, Last modification date: 2023-11-22)

• Primary citation: Xu, Y.,Wang, Y.,Wang, Y.,Liu, K.,Peng, Y.,Yao, D.,Tao, H.,Liu, H.,Song, G.; Mutagenesis facilitated crystallization of GLP-1R.; Iucrj, 6:996-1006, 2019; PubMed: 31709055; DOI: 10.1107/S2052252519013496

Experimental method

X-RAY DIFFRACTION (2.8 Å)