6KJF

lovastatin esterase PcEST in complex with simvastatin

Summary for 6KJF

Entry DOI	10.2210/pdb6kjf/pdb
Descriptor	Pc15g00720 protein, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, Simvastatin acid, ... (4 entities in total)
Functional Keywords	family viii esterase, lovastatin hydrolysis, monacolin j, simvastatin, hydrolase
Biological source	Penicillium rubens Wisconsin 54-1255
Total number of polymer chains	2
Total formula weight	88428.15
Authors	Liang, Y.J.,Lu, X.F. (deposition date: 2019-07-22, release date: 2019-12-25, Last modification date: 2023-11-22)
Primary citation	Liang, Y.J.,Lu, X.F. Structural insights into the catalytic mechanism of lovastatin hydrolase J.Biol.Chem., 2019 Cited by DOI: 10.1074/jbc.RA119.011936 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation