6KIX
Cryo-EM structure of human MLL1-NCP complex, binding mode1
Summary for 6KIX
Entry DOI | 10.2210/pdb6kix/pdb |
EMDB information | 0694 |
Descriptor | Histone H3, Set1/Ash2 histone methyltransferase complex subunit ASH2, S-ADENOSYL-L-HOMOCYSTEINE, ... (14 entities in total) |
Functional Keywords | histone modification, nucleosome, mll, transcription, transcription-dna complex, transcription/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 14 |
Total formula weight | 379463.62 |
Authors | |
Primary citation | Xue, H.,Yao, T.,Cao, M.,Zhu, G.,Li, Y.,Yuan, G.,Chen, Y.,Lei, M.,Huang, J. Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573:445-449, 2019 Cited by PubMed: 31485071DOI: 10.1038/s41586-019-1528-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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