6KFT

MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1

Summary for 6KFT

• Entry DOI: 10.2210/pdb6kft/pdb
• Related: 6A38 6A3A 6A3B 6A3C 6A3E
• Descriptor: GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (10 entities in total)
• Functional Keywords: transport protein, nuclear export, complex, mutant, inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 160864.32

Authors

Sun, Q.,Li, Y. (deposition date: 2019-07-08, release date: 2020-07-15, Last modification date: 2023-11-22)

• Primary citation: Sui, M.,Xiong, M.,Li, Y.,Zhou, Q.,Shen, X.,Jia, D.,Gou, M.,Sun, Q.; Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor.; Int J Nanomedicine, 16:2833-2847, 2021; PubMed: 33883894; DOI: 10.2147/IJN.S266398

Experimental method

X-RAY DIFFRACTION (2.51 Å)