6KEY

Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)

Summary for 6KEY

• Entry DOI: 10.2210/pdb6key/pdb
• Descriptor: SPRY domain-containing SOCS box protein 2, Nitric oxide synthase, inducible (3 entities in total)
• Functional Keywords: spry domain-containing socs box protein, spsb2, inducible nitric oxide synthase, inos, e3 ubiquitin ligase, protein binding-inhibitor complex, protein binding/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 23971.78

Authors

Li, K.,Kuang, Z. (deposition date: 2019-07-05, release date: 2020-07-01, Last modification date: 2024-03-27)

• Primary citation: Li, K.,You, T.,Zhao, P.,Luo, Y.,Zhang, D.,Wei, H.,Wang, Y.,Yang, J.,Guan, X.,Kuang, Z.; Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase.; Nitric Oxide, 113-114:1-6, 2021; PubMed: 33862200; DOI: 10.1016/j.niox.2021.04.004

Experimental method

X-RAY DIFFRACTION (1.24 Å)