6KEY

Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)

6KEY の概要

• エントリーDOI: 10.2210/pdb6key/pdb
• 分子名称: SPRY domain-containing SOCS box protein 2, Nitric oxide synthase, inducible (3 entities in total)
• 機能のキーワード: spry domain-containing socs box protein, spsb2, inducible nitric oxide synthase, inos, e3 ubiquitin ligase, protein binding-inhibitor complex, protein binding/inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23971.78

構造登録者

Li, K.,Kuang, Z. (登録日: 2019-07-05, 公開日: 2020-07-01, 最終更新日: 2024-03-27)

• 主引用文献: Li, K.,You, T.,Zhao, P.,Luo, Y.,Zhang, D.,Wei, H.,Wang, Y.,Yang, J.,Guan, X.,Kuang, Z.; Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase.; Nitric Oxide, 113-114:1-6, 2021; PubMed: 33862200; DOI: 10.1016/j.niox.2021.04.004

実験手法

X-RAY DIFFRACTION (1.24 Å)