6KEB

Structure basis for Diltiazem block of a voltage-gated calcium channel

Summary for 6KEB

Entry DOI	10.2210/pdb6keb/pdb
Descriptor	Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ... (5 entities in total)
Functional Keywords	tetrameric, voltage-gated ion channel, voltage-gated calcium channel block, membrane protein, transport protein
Biological source	Arcobacter butzleri
Total number of polymer chains	4
Total formula weight	140565.16
Authors	Tang, L. (deposition date: 2019-07-04, release date: 2019-10-23, Last modification date: 2024-05-29)
Primary citation	Tang, L.,Gamal El-Din, T.M.,Lenaeus, M.J.,Zheng, N.,Catterall, W.A. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+Channel. Mol.Pharmacol., 96:485-492, 2019 Cited by PubMed: 31391290 DOI: 10.1124/mol.119.117531 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation